Prof Daniel Axelrod

Department of Physics, Biophysics, and Pharmacology University of Michigan at Ann Arbor

“Their (…) plans for developing a standard calibration slide for TIRF are very worthwhile. (…) The proposed calibration slide will clearly resolve (the) ambiguities (encountered in biological TIRF imaging) and allow for correction of data from unknown samples. (The) current collaboration with experts in nanofabrication and surface chemistry will likely lead to success.”

Dr Ralf Wolleschensky

Senior Principal, ZEISS Industrial & Quality Research, Jena, Germany

“We are excited about (…) (this) new nanoscopic axial ruler that will permit, for the non-specialist user, the calibration of fluorescence in terms of axial distance from the surface.

Such calibration is key for quantitative near-surface optical imaging, spectroscopy and sensing in general. Currently such calibration tools are not readily available and have to be built by experts. We are convinced that if you are successful, the new nanoscopic axial ruler can increase reproducibility and allow quantitative comparisons of results among different user lab, which will strongly change the way researchers will collaborate. We would be interested to see such standardization applied widely for various imaging arrangements and would consider using such calibration tools in our microscope.”

Dr Suat Topsu

President of ERGANEO

“This solution might (…) represent business opportunities in a growing number of fluorescence microscopies. The NANOSCALE project will permit to develop and validate in relevant customer environments the whole technological bricks necessary to build a full commercial offer”